Services

• Computer-Aided Drug Design (CADD)
  • ADMET Modeling and Prediction
  • De Novo Drug Design
  • Ligand Based Virtual Screening
    • Pharmacophore Modeling
    • Quantitative Structure-Activity Relationship (QSAR) Modeling
  • Quantum Mechanics for Target Selection
  • Structure-Based Virtual Screening
    • Homology Modeling
    • Molecular Docking
      • Antibody Antigen Docking
      • Protein Carbohydrate Docking
      • Protein Ligand Docking
      • Protein Lipid Docking
      • Protein Nucleic Acid Docking
      • Protein Peptide Docking
      • Protein Protein Docking
    • Molecular Dynamics Simulations
• DNA-Encoded Library Technology (DELT)
  • DELT Data Analysis
  • DNA-Encoded Library Design and Synthesis
  • DNA-Encoded Library Screening
  • High Throughput Sequencing
  • Hits Validation
  • Hit-to-Lead Optimization
  • Off-DNA Compound Re-synthesis
• Fragment-Based Screening
  • Fragment Libraries
  • Fragment-based Screening Methodologies
    • DSC for Protein Characterization
    • X-Ray Crystallography for Hit Confirmation
  • Fragment-to-Lead
• High Content Screening (HCS)
  • High Content Analysis
  • High Content Imaging (HCI)
  • Phenotypic Assays
• High Throughput Screening (HTS)
  • Automated HTS Platform
  • Biochemical assays in Hit Characterization
  • Biophysical Assays in Hit Characterization
    • BLI for Affinity-based Hit Screening
    • CD Spectrometry for Protein Structure Determination
    • ITC for Binding Assessment
    • MS for Structure Confirmation
      • AS-MS for Binding Interactions Evaluation
      • CE-MS for Target Characterization
      • GC-MS for Target Characterization
      • HPLC-MS for Target Structure Confirmation
      • LC-MS for Target Separation and Detection
    • MT for Binding Affinity Measurement
    • NMR Spectrometry for Tareget identification and Characterization
    • SPR Spectrometrys for Structure Determination
    • TSA for Protein's Stability Evaluation
  • Cellular assays in Hit Characterization
    • CRISPR Cas9 Gene Editing for Target Identification and Validation
  • Drug Repurposing
  • Hit Screening
  • HTS Assay Development
  • HTS Compounds Libraries
  • HTS Data Management
• Virtual Screening (VS)
  • Machine Learning in Target Prediction
    • BKD for Taget Identification
    • SVM for Lead Discovery
  • Structural and Ligand Similarity-based Hybrid Method
  • Virtual Compound Libraries

One-stop

Drug Discovery Services

• Experienced and qualified scientists functioning as project managers or study director
• Independent quality unit assuring regulatory compliance
• Methods validated per ICH GLP/GMP guidelines
• Rigorous sample tracking and handling procedures to prevent mistakes
• Controlled laboratory environment to prevent a whole new level of success